SEQC Spanish Society of Laboratory Medicine

Spanish Society of Laboratory Medicine

Dr. Luis García de Guadiana receives award for best clinical research article published in 2021 in the European Journal of Clinical Investigation.

04/07/2022

Within the context of the Congress of the European Society for Clinical Investigation

Dr. Luis García de Guadiana receives award for best clinical research article published in 2021 in the European Journal of Clinical Investigation.
Figure 1. Dr. Luis García de Guadiana Romualdo

- Dr. Luis García de Guadiana Romualdo is a specialist in the Clinical Analysis Service of the Santa Lucía University Hospital (Cartagena) and a member of the Commission of Biological Magnitudes related to Medical Emergencies of the SEQCML.

- The award-winning article confirmed the high incidence of myocardial damage in COVID-19 patients.

- Troponin, measured in the first 24 hours of admission, was a useful tool for risk stratification, being the variable that contributed the most information to the final predictive model.

Madrid, June 17, 2022. During the recent Congress of the European Society for Clinical Investigation (ESCI), held in Bari from June 8 to 10, the article “Cardiac troponin and COVID-19 severity: Results from BIOCOVID study”, whose lead author is Dr. Luis García de Guadiana Romualdo, a specialist in the Clinical Analysis Service of the Santa Lucía University Hospital (Cartagena) and a member of the SEQCML Commission on Biological Magnitudes related to Medical Emergencies, received the award for best clinical research article published during the year 2021 in the European Journal of Clinical Investigation.

This article is one of three manuscripts published in international journals based on the data obtained in the BIOCOVID Multicenter Registry, an initiative of Laboratory Medicine professionals in Spain in which 32 hospitals from 9 autonomous communities participated and which received the patronage of the Spanish Society of Laboratory Medicine (SEQCML), among other societies. The main objective of this study was to evaluate the usefulness of a series of biochemical, hematometric, and coagulation markers, readily available in an emergency room laboratory, for risk stratification in COVID-19 patients who required hospital admission during the first wave of the pandemic in our country.

At the award ceremony, Dr. García de Guadiana Romualdo, in addition to thanking all the professionals involved in the study for their collaboration, explained that the objectives of said study were to assess the incidence of myocardial damage, defined by the concentration of troponin, in the study population, and to analyze the association of said damage with hospital mortality, as well as the possible influence of the use of cut-off points stratified by sex, as recommended by the IFCC (International Federation of Clinical Chemistry).

The study, which included 1,280 patients, confirmed the high incidence of myocardial damage in COVID-19 patients, which was higher in the subgroup of patients in which troponin T was used as an indicator. The use of cut-off points stratified by sex slightly increased the percentage of patients with myocardial damage. In addition, troponin, measured in the first 24 hours of admission, was a useful tool for risk stratification, being the variable that provided the most information to the final predictive model.